Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ATF4 | P18848 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31162985 | 0.88 | MAPT (0.39) | ALOX5APFEN1SLC6A4HTR2AKCNH2 | |
| SCHEMBL23216195 | 0.86 | KDM4E (0.45) | GPR84KCNH2LMNAKDM4E | |
| SCHEMBL29512405 | 0.86 | KDM4E (0.45) | GPR84KCNH2LMNAKDM4E | |
| SCHEMBL19284539 | 0.79 | HSP90AB1 (0.34) | KCNH2DGAT1LMNAKDM4E | |
| SCHEMBL2131444 | 0.79 | CYP11B1 (0.44) | — | |
| SCHEMBL4678900 | 0.78 | ALOX5AP (0.36) | ALOX5APFEN1DGAT1 | |
| SCHEMBL15876100 | 0.77 | LMNA (0.35) | ALOX5APFEN1HRH3DGAT1LMNA | |
| SCHEMBL16355981 | 0.77 | KDM4E (0.34) | LMNAKDM4E | |
| SCHEMBL5579942 | 0.77 | MAPT (0.42) | ALOX5APFEN1LMNAKDM4E | |
| SCHEMBL2137336 | 0.76 | AR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217515-A1 | HETEROCYCLIC RING-SUBSTITUTED AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海复宏汉霖生物技术股份有限公司 | 2024-10-24 | — | — | WO | disclosed |