Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 16/20 | 0.38 |
| ▸ | UGCG | Q16739 | 14/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 14/20 | 0.38 |
| ▸ | LCT | P09848 | 4/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163785 | 0.89 | GBA1 (0.43) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163917 | 0.85 | UGCG (0.49) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163863 | 0.83 | GBA1 (0.49) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163832 | 0.83 | GUSB (0.40) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163919 | 0.82 | GBA1 (0.43) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163687 | 0.81 | UGCG (0.48) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163690 | 0.81 | GBA1 (0.48) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163689 | 0.81 | GUSB (0.43) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163686 | 0.81 | GBA1 (0.48) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163701 | 0.81 | UGCG (0.48) | GBA1UGCGGBA2LCTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179491-A1 | GBA1 AND GCS DUAL MODULATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-09-06 | — | — | WO | disclosed |