SCHEMBL31163690

SCHEMBL31163690

Cc1ccc(COC[C@H](F)CCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)C2)cc1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GBA1 P04062 16/20 0.48
▸ UGCG Q16739 16/20 0.48
▸ GBA2 Q9HCG7 16/20 0.48
▸ GAA P10253 1/20 0.43
▸ GUSB P08236 2/20 0.40
▸ LCT P09848 2/20 0.38
▸ SI P14410 2/20 0.38
▸ MGAM O43451 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31163686 1.00 GBA1 (0.48) GBA1UGCGGBA2GAAGUSB
SCHEMBL31163689 0.91 GUSB (0.43) GBA1UGCGGBA2GUSBLCT
SCHEMBL31163699 0.91 GUSB (0.43) GBA1UGCGGBA2GUSBLCT
SCHEMBL31163917 0.89 UGCG (0.49) GBA1UGCGGBA2GAAGUSB
SCHEMBL31163810 0.89 GUSB (0.38) GBA1UGCGGBA2GUSBLCT
SCHEMBL31163877 0.89 GUSB (0.44) GBA1UGCGGBA2GAAGUSB
SCHEMBL31163701 0.88 UGCG (0.48) GBA1UGCGGBA2GAAGUSB
SCHEMBL31163687 0.88 UGCG (0.48) GBA1UGCGGBA2GAAGUSB
SCHEMBL31163863 0.88 GBA1 (0.49) GBA1UGCGGBA2GAALCT
SCHEMBL31163925 0.88 GUSB (0.46) GBA1UGCGGBA2GAAGUSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673215-A1 GBA1 AND GCS DUAL MODULATOR ONO Pharmaceutical Co., Ltd. (JP) 2026-01-07 — — EP claimed
WO-2024179491-A1 GBA1 AND GCS DUAL MODULATOR ONO PHARMACEUTICAL CO., LTD. (JP) 2024-09-06 — — WO claimed
WO-2024179491-A1 GBA1 AND GCS DUAL MODULATOR ONO PHARMACEUTICAL CO., LTD. (JP) 2024-09-06 — — WO disclosed
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