Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GCK | P35557 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15880606 | 0.90 | GRAMD1A (0.48) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL12199715 | 0.88 | GRAMD1A (0.46) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL12199718 | 0.88 | GRAMD1A (0.51) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL12199719 | 0.86 | GRAMD1A (0.44) | GRAMD1AADORA1MAPTGCK | |
| SCHEMBL30717625 | 0.84 | GRAMD1A (0.44) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL30717561 | 0.83 | GRAMD1A (0.43) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL12761195 | 0.82 | GRAMD1A (0.53) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL17993838 | 0.82 | GRAMD1A (0.53) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL165650 | 0.82 | GRAMD1A (0.53) | GRAMD1AADORA1MAPTGCKKDM4E | |
| SCHEMBL31748905 | 0.81 | GRM5 (0.42) | GRAMD1AADORA1MAPTGCKOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024213089-A1 | SUBSTITUTED DIHYDROTHIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海壹迪生物技术有限公司 | 2024-10-17 | — | — | WO | disclosed |