Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062085 | 0.88 | NR5A2 (0.50) | SMN1; SMN2KDM4CNR5A2KMT2AALDH1A1 | |
| SCHEMBL6304847 | 0.86 | KDM4C (0.40) | KDM4CNR5A2KMT2AALDH1A1MCHR1 | |
| Lithium Ion SCHEMBL31165573 | 0.84 | KDM4C (0.39) | KDM4CNR5A2KMT2AALDH1A1MCHR1 | |
| SCHEMBL6302882 | 0.83 | KDM4C (0.40) | KDM4CNR5A2KMT2AALDH1A1MCHR1 | |
| SCHEMBL31165671 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2KDM4CKMT2AALDH1A1POLB | |
| SCHEMBL27166533 | 0.78 | ACKR3 (0.47) | SMN1; SMN2KDM4CALDH1A1POLBKDM4E | |
| SCHEMBL15202347 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4CKMT2AALDH1A1POLB | |
| SCHEMBL6305129 | 0.77 | PARP1 (0.38) | SMN1; SMN2KDM4CKMT2AALDH1A1POLB | |
| SCHEMBL167425 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4CKMT2AALDH1A1POLB | |
| SCHEMBL1431755 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4CKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024218059-A1 | NEW α4β7 INHIBITORS | EVOTEC INTERNATIONAL GMBH (DE) | 2024-10-24 | — | — | WO | disclosed |