Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | CTPS1 | P17812 | 7/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.32 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167131 | 0.82 | TSHR (0.35) | BRAFRAF1MAP2K1CYP2C9MAP2K2 | |
| SCHEMBL31166785 | 0.77 | CKS1B (0.38) | SCN9AMAP4K1CTPS1PRMT6BRAF | |
| SCHEMBL28821097 | 0.75 | BACE1 (0.38) | BRD4CYP2C9 | |
| SCHEMBL31166925 | 0.73 | AAK1 (0.40) | CYP17A1 | |
| SCHEMBL20607539 | 0.73 | BACE1 (0.33) | — | |
| SCHEMBL958916 | 0.70 | AAK1 (0.33) | — | |
| SCHEMBL31320116 | 0.68 | MAPK1 (0.33) | — | |
| SCHEMBL31166797 | 0.68 | CKS1B (0.36) | SCN9ACTPS1PRMT6BRAFBRD4 | |
| SCHEMBL26985302 | 0.68 | NPC1 (0.34) | — | |
| SCHEMBL28398307 | 0.67 | AOC3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |