Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320121 | 0.86 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL31320123 | 0.81 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL28821097 | 0.77 | BACE1 (0.38) | — | |
| SCHEMBL28821088 | 0.77 | TGFBR1 (0.36) | — | |
| SCHEMBL31166925 | 0.74 | AAK1 (0.40) | — | |
| SCHEMBL31167131 | 0.70 | TSHR (0.35) | — | |
| SCHEMBL31166751 | 0.68 | SCN9A (0.35) | — | |
| SCHEMBL18646360 | 0.66 | AOC3 (0.32) | — | |
| SCHEMBL31320125 | 0.63 | ABL1 (0.44) | MAPK1 | |
| SCHEMBL31320113 | 0.63 | KDR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |