SCHEMBL31166845

SCHEMBL31166845

Fc1cc(Br)c(OCc2ccccc2)cc1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KDM1A O60341 7/20 0.48
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
MAOB P27338 1/20 0.45
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
NPC1 O15118 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
PTPN1 P18031 1/20 0.43
PTGER1 P34995 1/20 0.43
HTR1A P08908 1/20 0.42
DRD2 P14416 1/20 0.42
S1PR5 Q9H228 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16636496 0.91 RAB9A (0.50) RAB9ASMN1; SMN2KDM1AHTR2AHTR2C
SCHEMBL27262835 0.91 PTPN1 (0.47) RAB9ASMN1; SMN2KDM1AMAOBMAPK1
SCHEMBL416139 0.90 KDM1A (0.48) RAB9ASMN1; SMN2KDM1AMAOBMAPT
SCHEMBL30221893 0.86 KDM1A (0.48) RAB9ASMN1; SMN2KDM1AMAOBMAPT
SCHEMBL20521874 0.86 KDM1A (0.48) RAB9ASMN1; SMN2KDM1AMAOBMAPT
SCHEMBL21835660 0.85 MAPT (0.49) RAB9ASMN1; SMN2KDM1AMAOBMAPT
SCHEMBL20922980 0.85 RAB9A (0.46) RAB9ASMN1; SMN2KDM1AHTR2AHTR2C
SCHEMBL31611455 0.84 RAB9A (0.48) RAB9ASMN1; SMN2KDM1AFFAR1FFAR4
SCHEMBL20639243 0.83 MRGPRX4 (0.45) RAB9ASMN1; SMN2KDM1AHTR2AHTR2C
SCHEMBL29564439 0.83 MEN1 (0.44) RAB9AKDM1AMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698520-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF Gandeeva Therapeutics, Inc. (US) 2026-02-25 EP disclosed
WO-2024220708-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF GANDEEVA THERAPEUTICS, INC. (US) 2024-10-24 WO disclosed