SCHEMBL31167366

SCHEMBL31167366

C#Cc1cccc(Nc2ncnc3cc(OC)ccc23)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 15/20 0.73
FBP1 P09467 2/20 0.73
GAK O14976 2/20 0.73
ALDH1A1 P00352 1/20 0.73
MAPT P10636 1/20 0.73
KDR P35968 3/20 0.64
ABCG2 Q9UNQ0 3/20 0.64
ERBB2 P04626 2/20 0.64
PDGFRA P16234 2/20 0.64
LTK P29376 2/20 0.64
LRRK2 Q5S007 2/20 0.64
AURKB Q96GD4 2/20 0.64
ILK Q13418 2/20 0.64
LMNA P02545 2/20 0.64
RET P07949 2/20 0.64
SRC P12931 2/20 0.64
PLK4 O00444 1/20 0.64
CIT O14578 1/20 0.64
AURKA O14965 1/20 0.64
EPHB6 O15197 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1507676 1.00 EGFR (0.73) EGFRFBP1GAKALDH1A1MAPT
SCHEMBL31167368 1.00 EGFR (0.73) EGFRFBP1GAKALDH1A1MAPT
Hydrochloric Acid SCHEMBL1507772 0.99 EGFR (0.72) EGFRFBP1GAKALDH1A1MAPT
Hydrochloric Acid SCHEMBL8686177 0.93 EGFR (0.64) EGFRFBP1GAKALDH1A1MAPT
Glycolic Acid SCHEMBL28823471 0.91 EGFR (0.62) EGFRFBP1GAKALDH1A1MAPT
SCHEMBL4354683 0.91 EGFR (0.73) EGFRFBP1GAKALDH1A1MAPT
Hydrochloric Acid SCHEMBL1507575 0.90 EGFR (0.72) EGFRFBP1GAKALDH1A1MAPT
SCHEMBL22336685 0.88 EGFR (0.79) EGFRFBP1GAKALDH1A1MAPT
SCHEMBL667895 0.85 EGFR (1.00) EGFRFBP1GAKALDH1A1MAPT
SCHEMBL15051921 0.84 BRAF (0.72) EGFRFBP1GAKALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852129-A Preparation method and application of triazole feed additive with anti-inflammatory activity designed based on deep learning technology 河南湾流生物科技有限公司 2024-10-29 CN claimed
CN-118852129-A Preparation method and application of triazole feed additive with anti-inflammatory activity designed based on deep learning technology 河南湾流生物科技有限公司 2024-10-29 CN disclosed