Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 6/20 | 0.44 |
| ▸ | TYK2 | P29597 | 11/20 | 0.43 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511719 | 0.84 | MAP3K5 (0.54) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL25260883 | 0.84 | MAP3K5 (0.54) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL26599153 | 0.81 | TYK2 (0.51) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL31185798 | 0.81 | TYK2 (0.51) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL26599338 | 0.78 | TYK2 (0.47) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL26599329 | 0.78 | TYK2 (0.47) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL31185868 | 0.78 | TYK2 (0.47) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL21329796 | 0.73 | TYK2 (0.52) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL21330074 | 0.71 | L3MBTL1 (0.41) | MAP3K5TYK2JAK1HTR1AHTR1D | |
| SCHEMBL21349538 | 0.70 | L3MBTL1 (0.41) | MAP3K5TYK2JAK1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217523-A1 | SELECTIVE TKY2 INHIBITORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-10-24 | — | — | WO | disclosed |