Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31168261 | 1.00 | FFAR1 (0.51) | FFAR1USP30ALDH1A1MEN1GLA | |
| SCHEMBL31168267 | 1.00 | FFAR1 (0.51) | FFAR1USP30ALDH1A1MEN1GLA | |
| SCHEMBL12439731 | 0.86 | FFAR1 (0.50) | FFAR1USP30CHRM2CHRM4CHRM1 | |
| SCHEMBL15726271 | 0.85 | FFAR1 (0.48) | FFAR1USP30CHRM2CHRM4CHRM1 | |
| SCHEMBL15377252 | 0.84 | FFAR1 (0.50) | FFAR1USP30SCDSCD5USP2 | |
| SCHEMBL15416755 | 0.84 | FFAR1 (0.53) | FFAR1ALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL12993498 | 0.83 | FFAR1 (0.49) | FFAR1USP30SCDSCD5 | |
| SCHEMBL2799598 | 0.83 | USP30 (0.51) | FFAR1USP30KDM1A | |
| SCHEMBL992468 | 0.83 | FFAR1 (0.52) | FFAR1ALDH1A1CHRM2CHRM4CHRM3 | |
| SCHEMBL24779751 | 0.83 | USP30 (0.47) | FFAR1USP30ALDH1A1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719592-A1 | BICYCLIC COMPOUNDS FOR KETOHEXOKINASE INHIBITION | Centennial Therapeutics, LLC (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4695239-A1 | DISUBSTITUTED PYRIMIDINE COMPOUNDS FOR KETOHEXOKINASE INHIBITION | Centennial Therapeutics, LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024249612-A1 | BICYCLIC COMPOUNDS FOR KETOHEXOKINASE INHIBITION | CENTENNIAL THERAPEUTICS, LLC (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024216034-A1 | DISUBSTITUTED PYRIMIDINE COMPOUNDS FOR KETOHEXOKINASE INHIBITION | CENTENNIAL THERAPEUTICS, LLC (US) | 2024-10-17 | — | — | WO | disclosed |