SCHEMBL2799598

SCHEMBL2799598

CC(C)(C)OC(=O)N1CCC(Cn2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 1/20 0.51
FFAR1 O14842 1/20 0.49
FAAH O00519 1/20 0.42
BACE1 P56817 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PKM P14618 1/20 0.41
GPR119 Q8TDV5 9/20 0.40
KDM1A O60341 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15749273 0.94 USP30 (0.54) USP30FFAR1FAAHBACE1KDM4E
SCHEMBL22776955 0.91 USP30 (0.50) USP30FFAR1FAAHKDM4EPKM
SCHEMBL25209448 0.90 USP30 (0.46) USP30FFAR1FAAHGPR119
SCHEMBL25615939 0.90 USP30 (0.46) USP30FFAR1FAAHGPR119
SCHEMBL12101515 0.90 FFAR1 (0.51) USP30FFAR1BACE1
SCHEMBL30175048 0.88 USP30 (0.50) USP30FFAR1BACE1KDM1A
SCHEMBL29339937 0.88 USP30 (0.50) USP30FFAR1BACE1KDM1A
SCHEMBL2795787 0.88 USP30 (0.50) USP30FFAR1BACE1KDM1A
SCHEMBL15379160 0.88 FFAR1 (0.51) USP30FFAR1FAAHKDM4EPKM
SCHEMBL31565525 0.86 FFAR1 (0.47) USP30FFAR1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288426-B1 QUINOXALINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS INC (US) 2026-02-04 EP disclosed
US-20250325677-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-23 US disclosed
US-20250320206-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 US disclosed
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. 2025-05-01 US disclosed
WO-2025081092-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS KOLM THERAPEUTICS INC. (US) 2025-04-17 WO disclosed
US-20240368181-A1 QUINOXALINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS, INC. (US) 2024-11-07 US disclosed
US-12122767-B2 Bicyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2024-10-22 US disclosed
WO-2024213125-A1 BRM SELECTIVE DEGRADATION AGENT AND USE THEREOF 南京再明医药有限公司 2024-10-17 WO disclosed
US-20240309008-A1 IMIDAZOPYRIDAZINE AND IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF INCYTE CORPORATION 2024-09-19 US disclosed
US-12030889-B2 Imidazopyridazine and imidazopyridine compounds and uses thereof INCYTE CORPORATION (US) 2024-07-09 US disclosed
US-20130039906-A1 PYRAZOLO[3,4-c]PYRIDINE COMPOUNDS AND METHODS OF USE F. HOFFMANN-LA ROCHE AG (CH) 2013-02-14 US disclosed
US-20130039906-A1 PYRAZOLO[3,4-c]PYRIDINE COMPOUNDS AND METHODS OF USE F. HOFFMANN-LA ROCHE AG (CH) 2013-02-14 US disclosed
EP-2155201-B1 QUINOXALINE DERIVATIVES AS INHIBITORS OF THE TYROSINE KINASE ACTIVITY OF JANUS KINASES NOVARTIS AG (CH) 2012-08-01 EP disclosed
US-8193189-B2 Quinoxaline derivatives as tyrosine kinase activity inhibitors NOVARTIS AG (CH) 2012-06-05 US disclosed
US-8193189-B2 Quinoxaline derivatives as tyrosine kinase activity inhibitors NOVARTIS AG (CH) 2012-06-05 US disclosed
US-8193189-B2 Quinoxaline derivatives as tyrosine kinase activity inhibitors NOVARTIS AG (CH) 2012-06-05 US disclosed
US-20100168062-A1 Quinoxaline Derivatives as Tyrosine Kinase Activity Inhibitors NOVARTIS AG 2010-07-01 US disclosed
US-20100168062-A1 Quinoxaline Derivatives as Tyrosine Kinase Activity Inhibitors NOVARTIS AG 2010-07-01 US disclosed
US-20100168062-A1 Quinoxaline Derivatives as Tyrosine Kinase Activity Inhibitors NOVARTIS AG 2010-07-01 US disclosed
WO-2009024825-A1 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS ASTRAZENECA AB (SE) 2009-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136578-A1 BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS AR, SHBG, FSHR USP30 1156/4885FFAR1 120/4885FAAH 2825/4885
US-20130039906-A1 PYRAZOLO[3,4-c]PYRIDINE COMPOUNDS AND METHODS OF USE PIM1, PIM3, PIM2 USP30 4610/4885FFAR1 2898/4885FAAH 4873/4885
US-20250325677-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 USP30 1139/4885FFAR1 515/4885FAAH 1632/4885
US-20100168062-A1 Quinoxaline Derivatives as Tyrosine Kinase Activity Inhibitors JAK2, JAK1, JAK3 USP30 1940/4885FFAR1 2789/4885FAAH 4450/4885
US-12030889-B2 Imidazopyridazine and imidazopyridine compounds and uses thereof ALK, ABL2, ACVR2A USP30 4365/4885FFAR1 2622/4885FAAH 3353/4885
US-12122767-B2 Bicyclic heterocycles as FGFR inhibitors FGFR3, FGFR1, FGFR2 USP30 4106/4885FFAR1 2111/4885FAAH 2187/4885
US-20240309008-A1 IMIDAZOPYRIDAZINE AND IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF ALK, ABL2, ACVR2A USP30 4365/4885FFAR1 2622/4885FAAH 3353/4885
US-20240368181-A1 QUINOXALINE DERIVATIVES AND USES THEREOF NQO2, NQO1, GLS USP30 4702/4885FFAR1 4356/4885FAAH 4478/4885
US-20250320206-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 USP30 1139/4885FFAR1 515/4885FAAH 1632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.