Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE8A | O60658 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979104 | 0.86 | TP53 (0.36) | MAPTPOLBTP53EGFRRXFP1 | |
| SCHEMBL31169375 | 0.80 | RXFP1 (0.42) | MAPTPOLBPDE8APDE4ATP53 | |
| SCHEMBL30979033 | 0.80 | MAPT (0.41) | MAPTPOLBPDE8APDE4ATP53 | |
| SCHEMBL31169398 | 0.79 | ABCG2 (0.47) | EGFR | |
| SCHEMBL31169427 | 0.77 | TP53 (0.36) | MAPTPOLBTP53EGFRRXFP1 | |
| SCHEMBL30979034 | 0.74 | GAA (0.40) | MAPTPOLBPDE4ATP53RXFP1 | |
| SCHEMBL30979068 | 0.73 | TP53 (0.38) | MAPTPOLBTP53EGFRNPY5R | |
| SCHEMBL30978993 | 0.71 | NPY5R (0.38) | MAPTNPY5R | |
| SCHEMBL30979107 | 0.71 | GSK3B (0.39) | MAPTPOLBNPY5R | |
| SCHEMBL30978951 | 0.70 | KDR (0.43) | MAPTTP53EGFRRXFP1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |