Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979104 | 0.91 | TP53 (0.36) | TP53POLBTDP1NPY5RKDM4E | |
| SCHEMBL30979013 | 0.81 | TP53 (0.43) | TP53POLBTDP1NPY5RKDM4E | |
| SCHEMBL30979106 | 0.79 | LATS1 (0.43) | TP53POLBTDP1KDM4EBRD4 | |
| SCHEMBL30979014 | 0.78 | ABCG2 (0.52) | POLBEGFRMAPTPDE5A | |
| SCHEMBL30979068 | 0.78 | TP53 (0.38) | TP53POLBTDP1NPY5RKDM4E | |
| SCHEMBL31169441 | 0.77 | MAPT (0.37) | TP53POLBNPY5REGFRMAPT | |
| SCHEMBL30979076 | 0.76 | EGFR (0.42) | TP53POLBTDP1NPY5RKDM4E | |
| SCHEMBL30979115 | 0.75 | KDM4E (0.46) | TP53POLBTDP1KDM4EEGFR | |
| SCHEMBL30979029 | 0.75 | TP53 (0.39) | TP53POLBTDP1NPY5RKDM4E | |
| SCHEMBL30979016 | 0.74 | NPY5R (0.47) | TP53POLBNPY5RKDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |