SCHEMBL31169729

SCHEMBL31169729

CC(C)(C)OC(=O)[C@@H](Cc1cccc(Br)c1)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 7/20 0.48
DPP4 P27487 1/20 0.48
MMP9 P14780 1/20 0.45
STS P08842 1/20 0.44
YAP1 P46937 2/20 0.43
OPRD1 P41143 1/20 0.42
CTSB P07858 1/20 0.42
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
NOTCH1 P46531 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25171518 1.00 GPR119 (0.48) GPR119DPP4MMP9STSYAP1
SCHEMBL25171515 1.00 GPR119 (0.48) GPR119DPP4MMP9STSYAP1
SCHEMBL31293137 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL31588516 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL31588801 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL31588998 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL31291046 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL31588908 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL22764958 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1
SCHEMBL31589057 0.94 GPR119 (0.47) GPR119DPP4MMP9STSYAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042847-A1 SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-02-06 US disclosed
EP-4428129-A1 SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF Tuojie Biotech (Shanghai) Co., Ltd. (CN) 2024-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042847-A1 SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF SLC5A2, PAH, TGFB2 GPR119 265/4885DPP4 35/4885MMP9 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.