SCHEMBL31170844

SCHEMBL31170844

CO[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 15/20 0.54
WDR77 Q9BQA1 14/20 0.54
ADK P55263 1/20 0.50
ADORA2A P29274 1/20 0.50
METTL3 Q86U44 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731888 1.00 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL6841557 1.00 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL12154748 0.87 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL474831 0.87 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL12150851 0.87 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL14154371 0.87 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL16174495 0.87 PRMT5 (0.54) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL6841559 0.87 ADK (0.56) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL12150845 0.87 ADK (0.56) PRMT5WDR77ADKADORA2AMETTL3
SCHEMBL731889 0.87 ADK (0.56) PRMT5WDR77ADKADORA2AMETTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852299-A 7-Denitrification-2' -methoxy adenosine phosphoramidite monomer and synthetic method thereof 江苏合甘元生物科技有限公司 2024-10-29 CN claimed
CN-118852299-A 7-Denitrification-2' -methoxy adenosine phosphoramidite monomer and synthetic method thereof 江苏合甘元生物科技有限公司 2024-10-29 CN disclosed