Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22281403 | 0.93 | PDE4A (0.38) | MAPTMAPK1LMNATP53THRB | |
| SCHEMBL22281226 | 0.91 | PDE2A (0.37) | MAPTMAPK1LMNATHRBNTRK1 | |
| SCHEMBL22281227 | 0.90 | P2RX7 (0.39) | MAPK1NTRK1BRD4CREBBPBDKRB1 | |
| SCHEMBL22280891 | 0.89 | MAPK1 (0.38) | MAPTMAPK1LMNATHRBNTRK1 | |
| SCHEMBL23343385 | 0.89 | BRD4 (0.39) | MAPTMAPK1NTRK1BRD4CREBBP | |
| SCHEMBL22281222 | 0.89 | MAPK1 (0.37) | MAPTMAPK1LMNATHRBNTRK1 | |
| SCHEMBL22281225 | 0.89 | BRD4 (0.37) | MAPTMAPK1LMNATHRBNTRK1 | |
| SCHEMBL22280892 | 0.89 | MAPT (0.40) | MAPTMAPK1LMNATP53NTRK1 | |
| SCHEMBL22281232 | 0.88 | BDKRB1 (0.37) | MAPK1LMNANTRK1BRD4CREBBP | |
| SCHEMBL22281381 | 0.88 | PDE2A (0.36) | MAPTMAPK1NTRK1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024213752-A1 | LONG-TERM PREVENTION AND/OR TREATMENT OF A DISEASE BY SLO-1 INHIBITORS | ELANCO ANIMAL HEALTH GMBH (DE) | 2024-10-17 | — | — | WO | disclosed |