Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KAT7 | O95251 | 3/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172622 | 1.00 | CNR1 (0.36) | CNR1CNR2BRD4KLKB1MEN1 | |
| SCHEMBL31172526 | 0.90 | KLKB1 (0.39) | CNR1CNR2BRD4KLKB1MEN1 | |
| SCHEMBL31172570 | 0.85 | HTT (0.41) | CNR1CNR2BRD4KLKB1MEN1 | |
| SCHEMBL31172742 | 0.81 | ALDH1A1 (0.35) | CNR1CNR2BRD4KLKB1MEN1 | |
| SCHEMBL31172565 | 0.80 | KAT7 (0.40) | BRD4KLKB1MEN1KMT2AKAT7 | |
| SCHEMBL31516714 | 0.76 | KAT7 (0.50) | KAT7KAT6AKAT6B | |
| SCHEMBL31172590 | 0.73 | KLKB1 (0.41) | BRD4KLKB1MEN1KMT2AKAT7 | |
| SCHEMBL31172554 | 0.73 | KAT7 (0.42) | MEN1KMT2AKAT7KAT6AHTT | |
| SCHEMBL31172540 | 0.73 | HDAC1 (0.42) | BRD4KLKB1MEN1KMT2AKAT7 | |
| SCHEMBL31172572 | 0.72 | KLKB1 (0.41) | BRD4KLKB1MEN1KMT2AKAT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680226-A2 | ACYLSULFONAMIDE KAT6A INHIBITORS | Olema Pharmaceuticals, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024189598-A2 | ACYLSULFONAMIDE KAT6A INHIBITORS | OLEMA PHARMACEUTICALS, INC. (US) | 2024-09-19 | — | — | WO | disclosed |