SCHEMBL31173645

SCHEMBL31173645

COc1cnc(-c2cccc(OCC(=O)NC(C)(C)C)c2)nc1Nc1ccc(=O)[nH]c1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 12/20 0.51
▸ SLC2A3 P11169 12/20 0.51
▸ ROCK2 O75116 8/20 0.46
▸ ROCK1 Q13464 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27249049 1.00 SLC2A1 (0.51) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248812 0.87 SLC2A1 (0.57) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248850 0.85 SLC2A1 (0.51) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248991 0.85 SLC2A1 (0.49) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL31173640 0.85 SLC2A1 (0.51) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248974 0.84 ROCK2 (0.57) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248893 0.82 SLC2A1 (0.50) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248888 0.80 SLC2A1 (0.56) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248869 0.79 SLC2A1 (0.55) SLC2A1SLC2A3ROCK2ROCK1
SCHEMBL27248767 0.79 SLC2A1 (0.51) SLC2A1SLC2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360085-A1 Glucose Uptake Inhibitors KADMON CORPORATION, LLC (US) 2024-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360085-A1 Glucose Uptake Inhibitors SLC2A3, SLC2A1, SLC2A4 SLC2A1 2/4885SLC2A3 1/4885ROCK2 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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