SCHEMBL31174009

SCHEMBL31174009

O=C1C(=O)c2c(ccc3ccccc23)-c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 2/20 1.00
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
RAB9A P51151 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
ALDH1A1 P00352 4/20 0.56
MAPT P10636 3/20 0.56
CES1 P23141 4/20 0.55
LMNA P02545 4/20 0.54
PTPRC P08575 4/20 0.54
S100A4 P26447 3/20 0.54
APAF1 O14727 3/20 0.54
NPC1 O15118 3/20 0.54
HTT P42858 3/20 0.54
GALK1 P51570 3/20 0.54
BLM P54132 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
MAPK1 P28482 2/20 0.54
TDP2 O95551 2/20 0.54
PLA2G1B P04054 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1055754 1.00 DNMT1 (1.00) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL29440308 0.96 DNMT1 (0.92) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL30375875 0.96 DNMT1 (0.92) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL2175783 0.96 DNMT1 (0.92) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL19230419 0.91 DNMT1 (0.83) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL7912417 0.90 DNMT1 (0.82) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL16144677 0.89 DNMT1 (0.80) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL183078 0.88 DNMT1 (0.78) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL29612224 0.88 DNMT1 (0.78) DNMT1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL29358121 0.88 DNMT1 (0.78) DNMT1MEN1KMT2ARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4677612-A1 METHODS FOR DETERMINING DRUG CANDIDATES mosaiques diagnostics & therapeutics AG (DE) 2026-01-14 EP disclosed
WO-2024184437-A1 METHODS FOR DETERMINING DRUG CANDIDATES MOSAIQUES DIAGNOSTICS AND THERAPEUTICS AG (DE) 2024-09-12 WO disclosed