Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 4/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 12/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174065 | 0.87 | F11 (0.36) | F11KLK1HDAC6NOTUMAOC3 | |
| SCHEMBL31174097 | 0.83 | F11 (0.38) | F11KLK1ARNOTUMGABRA2 | |
| SCHEMBL31252533 | 0.82 | F11 (0.38) | F11KLK1ARNOTUMGABRA2 | |
| SCHEMBL31174123 | 0.82 | NOTUM (0.42) | F11KLK1HDAC6NOTUMAOC3 | |
| SCHEMBL31174041 | 0.82 | F11 (0.39) | F11KLK1ARNOTUMGABRA2 | |
| SCHEMBL31174079 | 0.81 | NOTUM (0.37) | F11KLK1ARNOTUMGABRA2 | |
| SCHEMBL24633398 | 0.81 | F11 (0.44) | F11KLK1HDAC6AOC3 | |
| SCHEMBL31174118 | 0.81 | F11 (0.44) | F11KLK1HDAC6AOC3 | |
| SCHEMBL29839752 | 0.78 | F11 (0.40) | F11KLK1NOTUM | |
| SCHEMBL29839754 | 0.78 | F11 (0.40) | F11KLK1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737457-A1 | POLYSUBSTITUTED MACROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| CN-118852163-A | Macrocyclic compound containing heteroatoms, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |