Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | F11 | P03951 | 5/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174092 | 0.87 | NOTUM (0.37) | POLBTIPARPF11NOTUMTRPC5 | |
| SCHEMBL31174072 | 0.79 | F11 (0.33) | F11F2KLKB1NOTUM | |
| SCHEMBL31174061 | 0.78 | F11 (0.38) | F11KLKB1 | |
| SCHEMBL31174095 | 0.77 | F11 (0.34) | F11F2KLKB1NOTUM | |
| SCHEMBL31174062 | 0.76 | HTT (0.41) | POLBALDH1A1F11F2KLKB1 | |
| SCHEMBL31174059 | 0.76 | TYMS (0.34) | F11F2KLKB1NOTUM | |
| SCHEMBL31174096 | 0.76 | F11 (0.33) | F11F2KLKB1NOTUM | |
| SCHEMBL31174040 | 0.75 | ALDH2 (0.33) | F11F2KLKB1NOTUM | |
| SCHEMBL30994983 | 0.75 | F11 (0.38) | F11F2KLKB1NOTUM | |
| SCHEMBL31174108 | 0.74 | F11 (0.35) | F11F2KLKB1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852163-A | Macrocyclic compound containing heteroatoms, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |