Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.55 |
| ▸ | PDE6C | P51160 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | PDE8A | O60658 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | PDE6A | P16499 | 1/20 | 0.47 |
| ▸ | PDE6G | P18545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032052 | 0.84 | PDE5A (0.74) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL19518053 | 0.81 | PDE5A (0.66) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL2032429 | 0.80 | PDE5A (0.78) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL18069562 | 0.80 | PDE5A (0.65) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL22558019 | 0.79 | KMT2A (0.62) | PDE5APDE6CPDE3APDE3BPDE2A | |
| SCHEMBL29393046 | 0.79 | KMT2A (0.62) | PDE5APDE6CPDE3APDE3BPDE2A | |
| SCHEMBL29707546 | 0.78 | PDE5A (0.77) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL145682 | 0.78 | PDE5A (0.77) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL28416630 | 0.77 | PDE5A (0.76) | PDE5APDE6CHDAC1HDAC6HDAC2 | |
| SCHEMBL18686087 | 0.77 | PDE5A (0.56) | PDE5APDE6CHDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515676-A | Synthetic method and application of cabazitaxel analogue | 湖北省食品质量安全监督检验研究院 | 2024-08-20 | — | — | CN | disclosed |