Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.87 |
| ▸ | INSR | P06213 | 6/20 | 0.87 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.87 |
| ▸ | IGF1R | P08069 | 5/20 | 0.87 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.87 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.87 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.87 |
| ▸ | EGFR | P00533 | 3/20 | 0.87 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.87 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.87 |
| ▸ | CDC7 | O00311 | 1/20 | 0.87 |
| ▸ | PLK4 | O00444 | 1/20 | 0.87 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.87 |
| ▸ | AURKA | O14965 | 1/20 | 0.87 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.87 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.87 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.87 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.87 |
| ▸ | JAK2 | O60674 | 1/20 | 0.87 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29730430 | 0.93 | PTK2 (1.00) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL29378728 | 0.93 | PTK2 (1.00) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL375524 | 0.93 | PTK2 (1.00) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL31174596 | 0.91 | ULK1 (0.87) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL375436 | 0.91 | MAPK9 (0.86) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL17544456 | 0.90 | PTK2 (0.94) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL31174595 | 0.88 | PTK2 (0.82) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL31174581 | 0.88 | ULK1 (0.72) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL16385715 | 0.88 | MAPK9 (0.80) | ALKINSRPTK2IGF1RMAPK9 | |
| SCHEMBL3775588 | 0.86 | MAPK10 (0.86) | ALKINSRPTK2IGF1RMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772064-A | Pyrimidine compound containing nitrogen methoxy benzamide and preparation method and application thereof | 贵州大学 | 2024-10-15 | — | — | CN | disclosed |