Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 15/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806806 | 1.00 | SLC10A2 (0.44) | SLC10A2NR1H4CYP3A4CYP2C9NFKB1 | |
| SCHEMBL6783221 | 0.96 | SLC10A2 (0.45) | SLC10A2NR1H4 | |
| SCHEMBL14559700 | 0.96 | SLC10A2 (0.45) | SLC10A2NR1H4 | |
| SCHEMBL5221836 | 0.96 | SLC10A2 (0.45) | SLC10A2NR1H4 | |
| SCHEMBL7093163 | 0.94 | SLC10A2 (0.41) | SLC10A2NR1H4MEN1KMT2AKDM4E | |
| SCHEMBL6632483 | 0.94 | NR1H4 (0.47) | SLC10A2NR1H4CYP3A4CYP2C9NFKB1 | |
| SCHEMBL14570802 | 0.93 | NR1H4 (0.39) | SLC10A2NR1H4LMNA | |
| SCHEMBL3814994 | 0.91 | SLC10A2 (0.37) | SLC10A2NR1H4MEN1KMT2APTPN1 | |
| SCHEMBL31051357 | 0.91 | SLC10A2 (0.42) | SLC10A2NR1H4 | |
| SCHEMBL22286569 | 0.91 | SLC10A2 (0.42) | SLC10A2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114786773-B | Benzothiazaheterocycles Heptatriene compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-10-18 | — | — | CN | claimed |
| CN-114786773-B | Benzothiazaheterocycles Heptatriene compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-10-18 | — | — | CN | disclosed |