Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31122438 | 1.00 | NPSR1 (0.58) | NPSR1NPC1RAB9AHSD17B10SPHK1 | |
| SCHEMBL18591277 | 0.83 | NPSR1 (0.64) | NPSR1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL31122478 | 0.79 | SPHK1 (0.53) | NPC1RAB9ASPHK1GAA | |
| SCHEMBL10598470 | 0.78 | CYP1A2 (0.53) | NPC1RAB9ASPHK1LMNAMEN1 | |
| SCHEMBL24543239 | 0.78 | KHK (0.79) | NPC1RAB9AHSD17B10SPHK1MEN1 | |
| Hydrochloric Acid SCHEMBL29677303 | 0.78 | KHK (0.78) | NPC1RAB9AHSD17B10SPHK1MEN1 | |
| SCHEMBL259383 | 0.77 | NPSR1 (0.78) | NPSR1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL12295117 | 0.77 | NPSR1 (0.63) | NPSR1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL29697282 | 0.77 | NPSR1 (0.63) | NPSR1NPC1RAB9AHSD17B10LMNA | |
| SCHEMBL10326684 | 0.77 | NPSR1 (0.63) | NPSR1NPC1RAB9AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182384-A1 | SUBSTITUTED PYRROLIDINE AND PYRROLIDINONE COMPOUNDS | CYTEIR THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |