Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Hydroxyurea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyguanidine SCHEMBL116225 | 0.71 | — | — | |
| Hydroxyguanidine SCHEMBL7265255 | 0.67 | — | — | |
| SCHEMBL2268982 | 0.67 | — | — | |
| SCHEMBL2268990 | 0.67 | — | — | |
| Hydroxyguanidine SCHEMBL5262447 | 0.67 | — | — | |
| SCHEMBL2268985 | 0.67 | — | — | |
| SCHEMBL12797837 | 0.63 | — | — | |
| SCHEMBL7828584 | 0.63 | — | — | |
| SCHEMBL407700 | 0.63 | — | — | |
| SCHEMBL16712317 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024181929-A1 | PRINTED POROUS ELASTOMERIC CONDUCTORS FOR STRETCHABLE ELECTRONICS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-09-06 | — | — | WO | disclosed |