Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.40 |
| ▸ | CYP8B1 | Q9UNU6 | 4/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653362 | 0.90 | DPP4 (0.49) | DPP4DPP9DPP7DPP8PARP1 | |
| SCHEMBL31177343 | 0.78 | DPP4 (0.33) | DPP4DPP9DPP7DPP8PARP1 | |
| SCHEMBL20099681 | 0.74 | P2RX7 (0.36) | DPP4DPP9DPP7DPP8P2RX7 | |
| SCHEMBL21253287 | 0.74 | P2RX7 (0.36) | DPP4DPP9DPP7DPP8P2RX7 | |
| SCHEMBL17596463 | 0.72 | P2RX7 (0.52) | P2RX7GPR119 | |
| SCHEMBL17596464 | 0.72 | P2RX7 (0.52) | P2RX7GPR119 | |
| SCHEMBL17596276 | 0.69 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL17596277 | 0.69 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL5648690 | 0.69 | P2RX7 (0.38) | DPP4DPP9DPP7DPP8CYP8B1 | |
| SCHEMBL3134930 | 0.68 | CYP8B1 (0.54) | DPP4DPP9DPP7DPP8CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024218503-A1 | SOLID FORMS OF AN ENZYME INHIBITOR AND SALTS THEREOF | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2024-10-24 | — | — | WO | disclosed |