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SCHEMBL3118151

SCHEMBL3118151

N#Cc1c(C(F)(F)F)cc(N)cc1C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 14/20 0.46
▸ KDM4E B2RXH2 14/20 0.46
▸ GAA P10253 13/20 0.46
▸ HPGD P15428 11/20 0.46
▸ GLA P06280 10/20 0.46
▸ TP53 P04637 1/20 0.46
▸ POLB P06746 2/20 0.45
▸ TSHR P16473 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.41
▸ KMT2A Q03164 5/20 0.39
▸ HTT P42858 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ MEN1 O00255 4/20 0.38
▸ LMNA P02545 3/20 0.38
▸ CRHBP P24387 1/20 0.38
▸ CRHR2 Q13324 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 4/20 0.37
▸ TDP1 Q9NUW8 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12144648 0.88 ALDH1A1 (0.41) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL1438722 0.86 KDM4E (0.47) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL12144654 0.86 GAA (0.41) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL27414564 0.82 ALDH1A1 (0.46) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL203549 0.82 KDM4E (0.46) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL7570304 0.79 ALDH1A1 (0.47) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL80564 0.77 KDM4E (0.55) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL30084378 0.77 ALDH1A1 (0.49) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL7576571 0.75 ALDH1A1 (0.41) ALDH1A1KDM4EGAAHPGDGLA
SCHEMBL18838831 0.75 ALDH1A1 (0.35) ALDH1A1KDM4EGAAHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126619-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE NOVALED GMBH (DE) 2024-06-20 — — WO disclosed
WO-2024061807-A1 ORGANIC ELECTRONIC DEVICE COMPRISING A CHARGE GENERATION LAYER NOVALED GMBH (DE) 2024-03-28 — — WO disclosed
WO-2024033322-A1 METAL COMPLEX, SEMICONDUCTOR LAYER COMPRISING A METAL COMPLEX AND ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2024-02-15 — — WO disclosed
WO-2023110888-A1 A CE(IV) METAL COMPLEX, AN ORGANIC ELECTRONIC DEVICE COMPRISING AN ANODE LAYER, A CATHODE LAYER AND A CHARGE GENERATION LAYER, WHEREIN THE CHARGE GENERATION LAYER COMPRISES A P-TYPE CHARGE GENERATION LAYER THAT COMPRISES THE CE(IV) METAL COMPLEX AND A N-TYPE CHARGE GENERATION LAYER NOVALED GMBH (DE) 2023-06-22 — — WO disclosed
EP-1697309-B1 BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES BASF SE (DE) 2014-04-23 — — EP disclosed
EP-2315760-B1 PIPERAZINE COMPOUNDS WITH HERBICIDAL EFFECT BASF SE (DE) 2013-03-06 — — EP disclosed
US-20100179172-A1 N-PHENYL-METHANAMINE DERIVATIVE AND PESTICIDE CONTAINING IT ISHIHARA SANGYO KAISHA , LTD. (JP) 2010-07-15 — — US disclosed
EP-1971581-B1 PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION BASF SE (DE) 2010-04-07 — — EP disclosed
EP-2172456-A1 N-PHENYL-METHANAMINE DERIVATIVE AND PEST CONTROL AGENT CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-07 — — EP disclosed
EP-1971580-B1 PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION BASF SE (DE) 2010-02-24 — — EP disclosed
WO-2000068210-A1 BENZOHETERO CYCLYLCYCLO HEXENONES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-11-16 — — WO disclosed
WO-2000064912-A1 PHOSPHORIC BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 — — WO disclosed
WO-2000035903-A2 THIOCHROMANOYL CYCLOHEXENONE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-06-22 — — WO disclosed
WO-2000014069-A1 CYCLOHEXENONQUINOLINOYL-DERIVATIVES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2000-03-16 — — WO disclosed
WO-1999059991-A1 PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-11-25 — — WO disclosed
EP-0958292-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-11-24 — — EP disclosed
WO-1999057111-A1 CYCLOHEXENONDIOXOTHIO CHROMANOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-11-11 — — WO disclosed
EP-0929548-A1 SUBSTITUTED CARBAMOYL TRIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-07-21 — — EP disclosed
WO-1998031682-A1 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-07-23 — — WO disclosed
WO-1998012193-A1 SUBSTITUTED CARBAMOYL TRIAZOLES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179172-A1 N-PHENYL-METHANAMINE DERIVATIVE AND PESTICIDE CONTAINING IT CHRM2, CHRM5, CHRM3 ALDH1A1 2887/4885KDM4E 1362/4885GAA 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.