Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118214 | 1.00 | PLA2G10 (0.47) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL8819340 | 0.84 | PLA2G10 (0.52) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL3103530 | 0.82 | GAA (0.50) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL3103541 | 0.82 | GAA (0.50) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL3105212 | 0.77 | GAA (0.65) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL3105199 | 0.77 | GAA (0.65) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL3111869 | 0.74 | GAA (0.50) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL3111866 | 0.74 | GAA (0.50) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL11267920 | 0.69 | PLA2G10 (0.60) | PLA2G10PLA2G5GAACYP3A4CYP2C19 | |
| SCHEMBL12408230 | 0.69 | PLA2G10 (0.60) | PLA2G10PLA2G5GAACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732605-B2 | Synthesis of diketopiperazines | NEREUS PHARMACEUTICALS, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-7732605-B2 | Synthesis of diketopiperazines | NEREUS PHARMACEUTICALS, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-7732605-B2 | Synthesis of diketopiperazines | NEREUS PHARMACEUTICALS, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-20060235226-A1 | Synthesis of diketopiperazines | BEYONDSPRING PHARMACEUTICALS, INC. | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235226-A1 | Synthesis of diketopiperazines | DHPS, COASY, TKT | PLA2G10 4625/4885PLA2G5 3674/4885GAA 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.