Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | FURIN | P09958 | 7/20 | 0.44 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29539249 | 0.89 | BMP1 (0.43) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30964332 | 0.88 | SLC15A2 (0.47) | FOLH1FURINSLC15A2 | |
| SCHEMBL31202999 | 0.88 | SLC15A2 (0.45) | FOLH1FURINSLC15A2 | |
| SCHEMBL31593363 | 0.87 | GRIN2D (0.48) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29373145 | 0.86 | SLC15A2 (0.49) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29777788 | 0.85 | FOLH1 (0.59) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30964333 | 0.85 | SLC15A2 (0.51) | FOLH1FURINSLC15A2 | |
| SCHEMBL30570968 | 0.84 | BACE1 (0.49) | FOLH1 | |
| SCHEMBL29463331 | 0.84 | FOLH1 (0.48) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30277937 | 0.83 | GRIN2D (0.48) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240350475-A1 | TRIGONELLINE MITIGATES CARDIOMYOPATHY CAUSED BY SARS-COV-2 SPIKE PROTEIN UNDER OBESITY | UNIVERSITY OF SOUTH CAROLINA (US) | 2024-10-24 | — | — | US | disclosed |