Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184607 | 0.92 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184788 | 0.88 | POLB (0.44) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184894 | 0.87 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184585 | 0.87 | CHKA (0.44) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184633 | 0.87 | POLB (0.43) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184647 | 0.87 | POLB (0.43) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31185002 | 0.86 | POLB (0.40) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184906 | 0.86 | ACHE (0.43) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184629 | 0.85 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184972 | 0.85 | POLB (0.44) | POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |