Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30870520 | 0.99 | POLB (0.57) | POLBULK1SMYD3ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28516334 | 0.99 | POLB (0.57) | POLBULK1SMYD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184396 | 0.92 | POLB (0.53) | POLBULK1SMYD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184635 | 0.92 | POLB (0.53) | POLBULK1SMYD3ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31185115 | 0.91 | POLB (0.52) | POLBULK1SMYD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184837 | 0.87 | POLB (0.58) | POLBALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL30870166 | 0.86 | POLB (0.64) | POLBALDH1A1SMN1; SMN2HPGDGRM4 | |
| SCHEMBL28500867 | 0.86 | POLB (0.64) | POLBALDH1A1SMN1; SMN2HPGDGRM4 | |
| SCHEMBL31184928 | 0.86 | POLB (0.57) | POLBALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL31184807 | 0.85 | POLB (0.63) | POLBALDH1A1SMN1; SMN2HPGDGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |