Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ULK1 | O75385 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184396 | 1.00 | POLB (0.53) | POLBULK1MAPTGRM4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31185115 | 0.99 | POLB (0.52) | POLBULK1MAPTGRM4ALDH1A1 | |
| SCHEMBL31184530 | 0.92 | POLB (0.58) | POLBULK1MAPTGRM4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30870520 | 0.91 | POLB (0.57) | POLBULK1MAPTGRM4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28516334 | 0.91 | POLB (0.57) | POLBULK1MAPTGRM4ALDH1A1 | |
| SCHEMBL31184805 | 0.84 | POLB (0.48) | POLBMAPTGRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184837 | 0.82 | POLB (0.58) | POLBMAPTGRM4ALDH1A1SMN1; SMN2 | |
| SCHEMBL30870166 | 0.82 | POLB (0.64) | POLBGRM4ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28500867 | 0.82 | POLB (0.64) | POLBGRM4ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL31184928 | 0.81 | POLB (0.57) | POLBGRM4ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |