Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185036 | 0.91 | POLB (0.41) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL31184934 | 0.88 | POLB (0.42) | POLBALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184727 | 0.84 | POLB (0.46) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL31184968 | 0.84 | POLB (0.36) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL31184397 | 0.84 | POLB (0.45) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL31184853 | 0.80 | POLB (0.41) | POLBALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184534 | 0.80 | POLB (0.39) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL31184653 | 0.80 | POLB (0.42) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL31184940 | 0.79 | CHKA (0.42) | POLBALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184472 | 0.79 | POLB (0.41) | POLBMAPTALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |