Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184914 | 0.88 | TYK2 (0.46) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184973 | 0.88 | POLB (0.44) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184972 | 0.88 | POLB (0.44) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184861 | 0.86 | POLB (0.43) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184573 | 0.86 | MALT1 (0.46) | TYK2ACHEBACE1POLBALDH1A1 | |
| SCHEMBL31184345 | 0.85 | POLB (0.42) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184954 | 0.85 | CHKA (0.43) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184820 | 0.85 | MAPK1 (0.49) | TYK2MAPTACHEBACE1POLB | |
| SCHEMBL31184791 | 0.85 | ACHE (0.44) | MAPTACHEBACE1POLBALDH1A1 | |
| SCHEMBL31184817 | 0.84 | MAPT (0.43) | TYK2MAPTACHEBACE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |