SCHEMBL31188560

SCHEMBL31188560

CCOc1ncccc1-c1ccc(N2CCN(C(=O)c3ccc(Cl)cc3C(F)(F)F)C[C@H]2CC)c(C(=O)NCC2=NCCN2)c1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MC2R Q01718 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21700595 1.00 MC2R (0.79) MC2R
SCHEMBL21700818 0.90 MC2R (0.84) MC2R
SCHEMBL31188946 0.90 MC2R (0.84) MC2R
SCHEMBL21700628 0.90 MC2R (0.79) MC2R
SCHEMBL21700781 0.90 MC2R (0.79) MC2R
SCHEMBL31188891 0.89 MC2R (0.83) MC2R
SCHEMBL21700686 0.89 MC2R (0.83) MC2R
SCHEMBL31188873 0.89 MC2R (0.80) MC2R
SCHEMBL21700885 0.89 MC2R (0.80) MC2R
SCHEMBL21700593 0.88 MC2R (1.00) MC2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533904-B Melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof 克林提克斯医药股份有限公司 2024-10-29 CN claimed
CN-112533904-B Melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof 克林提克斯医药股份有限公司 2024-10-29 CN disclosed