SCHEMBL31189134 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	USP2	O75604	1/20	0.47

▸	SMN1; SMN2	Q16637	1/20	0.47

▸	KMT2A	Q03164	1/20	0.44

▸	GPR119	Q8TDV5	5/20	0.42

▸	TSHR	P16473	2/20	0.40

▸	ALOX15	P16050	1/20	0.40

▸	ATM	Q13315	1/20	0.40

▸	TACR1	P25103	1/20	0.40

▸	CHRM2	P08172	1/20	0.40

▸	CHRM4	P08173	1/20	0.40

▸	CHRM1	P11229	1/20	0.40

▸	CHRM3	P20309	1/20	0.40

▸	RECQL	P46063	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15166535	0.87	USP2 (0.44)	USP2SMN1; SMN2KMT2AGPR119TSHR
SCHEMBL21273181	0.82	USP2 (0.40)	USP2SMN1; SMN2GPR119TSHRALOX15
SCHEMBL19852497	0.82	HRH3 (0.53)	KMT2AGPR119TSHRALOX15ATM
SCHEMBL21273179	0.82	USP2 (0.40)	USP2SMN1; SMN2GPR119TSHRALOX15
SCHEMBL467280	0.82	ATM (0.56)	KMT2AGPR119ATM
SCHEMBL3702583	0.82	ATM (0.56)	KMT2AGPR119ATM
SCHEMBL21273182	0.82	USP2 (0.40)	USP2SMN1; SMN2GPR119TSHRALOX15
SCHEMBL22911795	0.82	USP2 (0.44)	USP2SMN1; SMN2KMT2AGPR119TSHR
SCHEMBL3493829	0.82	GPR119 (0.44)	USP2SMN1; SMN2KMT2AGPR119TSHR
SCHEMBL4265096	0.81	KMT2A (0.55)	SMN1; SMN2KMT2AGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-118638118-A	Preparation method of 8-methyl-2, 8-diazaspiro [4.5] decane hydrochloride	南京合巨药业有限公司	2024-09-13	—	—	CN	disclosed