Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654967 | 0.89 | MAPT (0.50) | MAPTALDH1A1KDM4EALOX15LMNA | |
| SCHEMBL203439 | 0.89 | MAPT (0.50) | MAPTALDH1A1KDM4EALOX15LMNA | |
| SCHEMBL3771900 | 0.84 | PIM1 (0.48) | MAPTALDH1A1KDM4EALOX15LMNA | |
| SCHEMBL30693959 | 0.84 | PIM1 (0.48) | MAPTALDH1A1KDM4EALOX15LMNA | |
| SCHEMBL26627710 | 0.84 | MAPT (0.38) | MAPTALDH1A1KDM4EALOX15LMNA | |
| SCHEMBL19561508 | 0.79 | PIM1 (0.52) | MAPTALDH1A1KDM4EALOX15LMNA | |
| SCHEMBL29381559 | 0.78 | AHR (0.59) | MAPTALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL25611877 | 0.78 | AHR (0.59) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL259160 | 0.78 | AHR (0.59) | MAPTALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10122754 | 0.78 | CYP2A6 (0.48) | MAPTALDH1A1KDM4EALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852191-A | Compound taking fluoranthene double five-membered ring as parent nucleus and application thereof | 西安瑞联新材料股份有限公司 | 2024-10-29 | — | — | CN | disclosed |