SCHEMBL259160

SCHEMBL259160

Brc1ccc2c(c1)oc1ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.59
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
MAPT P10636 4/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
NPC1 O15118 4/20 0.48
RAB9A P51151 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
TNKS O95271 1/20 0.47
MAOA P21397 4/20 0.47
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46
PGAM1 P18669 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TP53 P04637 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381559 1.00 AHR (0.59) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL21890576 0.94 AHR (0.53) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL203439 0.89 MAPT (0.50) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL29654967 0.89 MAPT (0.50) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL31397562 0.88 MAOA (0.67) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL9851903 0.88 AHR (0.47) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL490127 0.88 MAOA (0.67) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL24073612 0.88 AHR (0.46) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL25620895 0.88 MAPT (0.55) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL29886872 0.87 MAPT (0.59) AHRMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894484-B Isoquinoline quinoline compound and preparation method and application thereof 烟台九目化学股份有限公司 2024-03-19 CN claimed
CN-115894484-A Isoquinoline compound and preparation method and application thereof 烟台九目化学股份有限公司 2023-04-04 CN claimed
CN-114957251-A High-performance photoelectric material, preparation method and organic electroluminescent device 烟台九目化学股份有限公司 2022-08-30 CN claimed
CN-109942527-A A kind of synthetic method of 3- bromine dibenzofurans 新乡市润宇新材料科技有限公司 2019-06-28 CN claimed
EP-4106028-B1 ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I), DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS COMPOUNDS OF FORMULA (I) NOVALED GMBH (DE) 2026-05-27 EP disclosed
US-12635408-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-19 US disclosed
CN-116813860-B Method for preparing polyurethane catalyst for rubber roller by taking camphene as starting material 沈阳东阳聚氨酯有限公司 2026-05-15 CN disclosed
US-12622132-B2 Light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-05-05 US disclosed
US-20260114177-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME MAT SCIENCE CO LTD (KR) 2026-04-23 US disclosed
US-20260114180-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY APPARATUS FUYANG SINEVA NEW MATERIAL TECH CO LTD (CN) 2026-04-23 US disclosed
US-20260090197-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2026-03-26 US disclosed
EP-3683208-B1 COMPOUND, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2026-03-25 EP disclosed
WO-1998009934-A1 MATRIX METALLOPROTEINASE INHIBITORS AND THEIR THERAPEUTIC USES WARNER-LAMBERT COMPANY (US) 1998-03-12 WO disclosed
EP-0764652-A1 Novel intermediates for the synthesis of bisphosphine compounds BAYER AG (DE) 1997-03-26 EP disclosed
US-5510503-A Bisphosphines for asymmetric hydrogenation catalysts BAYER AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
EP-0643065-A1 Novel bisphosphines for asymetric hydrogenation catalysts BAYER AG (DE) 1995-03-15 EP disclosed
US-5132420-A INTERMEDIATES FOR PREPARING 2-(SUBSTITUTED-DIBENZO-FURANYL AND DIBENZOTHIENYL) CARBAPENEM ANTIBACTERIAL AGENTS MERCK & CO., INC. (US) 1992-07-21 US disclosed
EP-0480715-A1 Intermediates for preparing 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents MERCK & CO. INC. (US) 1992-04-15 EP disclosed
US-5025008-A For methicillin resistant Staphylococcus aureus MERCK & CO., INC. (US) 1991-06-18 US disclosed
EP-0405774-A1 2-(substituted-dibenzofuranyl and dibenzothienyl)carbapenem antibacterial agents MERCK & CO. INC. (US) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622132-B2 Light-emitting device, light-emitting apparatus, electronic device, and lighting device CYBA, NFE2L2, AOX1 AHR 1124/4885MEN1 3212/4885KMT2A 888/4885
US-20260114180-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY APPARATUS AFF2, EFHD2, RPL22 AHR 85/4885MEN1 3387/4885KMT2A 3370/4885
US-20260090197-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE CHRM1, CHRM2, CRY1 AHR 15/4885MEN1 1178/4885KMT2A 2635/4885
US-20260114177-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME ARL1, ORC3, OR10J3 AHR 164/4885MEN1 3682/4885KMT2A 3079/4885
US-12635408-B2 Organic electroluminescence device and amine compound for organic electroluminescence device LEF1, MLLT1, NAP1L1 AHR 230/4885MEN1 3461/4885KMT2A 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.