Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.51 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14631680 | 1.00 | MAPK1 (0.51) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL5209867 | 0.81 | PDPK1 (0.68) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL8404437 | 0.79 | MAPK1 (0.54) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL24455090 | 0.76 | MAPK1 (0.51) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL12866145 | 0.76 | MAP2K4 (0.51) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL30548041 | 0.76 | MAPK1 (0.51) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL569660 | 0.76 | GAA (0.61) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL16724833 | 0.76 | PDPK1 (0.47) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL5952759 | 0.76 | PDPK1 (0.47) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 | |
| SCHEMBL28445675 | 0.76 | MAPK1 (0.60) | MAPK1MAP2K4MAPKAPK2MAPK6PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |