Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014193 | 1.00 | MAPT (0.54) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28692369 | 1.00 | MAPT (0.54) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28695551 | 1.00 | MAPT (0.54) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28712740 | 0.88 | TAAR1 (0.51) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28712741 | 0.88 | TAAR1 (0.51) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28711159 | 0.84 | RAB9A (0.64) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL22444717 | 0.84 | MAPT (0.46) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28711161 | 0.84 | RAB9A (0.64) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7176096 | 0.84 | MAPT (0.54) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7173058 | 0.84 | MAPT (0.54) | MAPTTAAR1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834236-A | Method for constructing P-chiral phosphonamide compound by nickel catalysis | 扬州大学 | 2024-10-25 | — | — | CN | disclosed |