Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 11/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191329 | 0.81 | ACACB (0.38) | SYK | |
| SCHEMBL17000213 | 0.80 | CYP2C19 (0.41) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| SCHEMBL15999345 | 0.80 | EPHX2 (0.43) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| SCHEMBL31191208 | 0.78 | CYP17A1 (0.38) | CYP2C9CYP2C19CYP17A1SYK | |
| SCHEMBL25208128 | 0.78 | EPHX2 (0.42) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| SCHEMBL16233076 | 0.77 | EPHX2 (0.41) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30931661 | 0.77 | EPHX2 (0.41) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL25208815 | 0.77 | EPHX2 (0.41) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30931579 | 0.76 | EPHX2 (0.40) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2716255 | 0.76 | EPHX2 (0.40) | CYP2C9CYP2C19CYP17A1EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702025-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024223715-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-31 | — | — | WO | disclosed |