Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 19/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191102 | 0.81 | CYP2C9 (0.43) | SYK | |
| SCHEMBL19343284 | 0.80 | ACACB (0.41) | ACACB | |
| SCHEMBL31191369 | 0.73 | RECQL (0.46) | ACACB | |
| SCHEMBL25202663 | 0.73 | ACACB (0.36) | ACACB | |
| SCHEMBL15034203 | 0.73 | RXRA (0.42) | ACACB | |
| SCHEMBL20606987 | 0.73 | ACACB (0.38) | ACACB | |
| SCHEMBL30281186 | 0.71 | KDM4C (0.47) | ACACB | |
| SCHEMBL28976365 | 0.71 | KDM4C (0.47) | ACACB | |
| SCHEMBL31191301 | 0.70 | SYK (0.33) | SYK | |
| SCHEMBL10141646 | 0.70 | ACACB (0.34) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702025-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024223715-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-31 | — | — | WO | disclosed |