Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192615 | 1.00 | USP30 (0.42) | USP30BRD4ALDH1A1MAPTMAPK1 | |
| SCHEMBL29504358 | 1.00 | USP30 (0.42) | USP30BRD4ALDH1A1MAPTMAPK1 | |
| SCHEMBL29504228 | 1.00 | USP30 (0.42) | USP30BRD4ALDH1A1MAPTMAPK1 | |
| SCHEMBL29504337 | 0.94 | USP30 (0.43) | USP30ALDH1A1MAPTMAPK1GPR174 | |
| SCHEMBL28706693 | 0.94 | USP30 (0.43) | USP30ALDH1A1MAPTMAPK1GPR174 | |
| SCHEMBL28706695 | 0.94 | USP30 (0.43) | USP30ALDH1A1MAPTMAPK1GPR174 | |
| SCHEMBL31192611 | 0.94 | USP30 (0.43) | USP30ALDH1A1MAPTMAPK1GPR174 | |
| SCHEMBL29504296 | 0.94 | USP30 (0.43) | USP30ALDH1A1MAPTMAPK1GPR174 | |
| SCHEMBL4648329 | 0.94 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1NPC1HTT | |
| SCHEMBL28695865 | 0.92 | USP30 (0.42) | USP30ALDH1A1MAPTMAPK1GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924296-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-09-17 | — | — | CN | disclosed |