Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 7/20 | 1.00 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.56 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18632516 | 0.80 | PDE3B (0.67) | PDE3BPDE3AGRIA1CACNG8JAK2 | |
| SCHEMBL18190673 | 0.80 | PDE3B (0.65) | PDE3BPDE3AGRIA1CACNG8CDC7 | |
| SCHEMBL20775334 | 0.79 | PDE3B (0.65) | PDE3BPDE3AGRIA1CACNG8CDC7 | |
| SCHEMBL1884345 | 0.79 | PDE3B (0.65) | PDE3BPDE3AGRIA1CACNG8DYRK1A | |
| SCHEMBL30832781 | 0.79 | PDE3B (0.65) | PDE3BPDE3AGRIA1CACNG8CDC7 | |
| SCHEMBL30832786 | 0.79 | PDE3B (0.65) | PDE3BPDE3AGRIA1CACNG8DYRK1A | |
| SCHEMBL29445971 | 0.78 | PDE3B (0.63) | PDE3BPDE3AGRIA1CACNG8CDC7 | |
| SCHEMBL18190751 | 0.76 | GRIA1 (0.69) | PDE3BPDE3AGRIA1CACNG8JAK2 | |
| SCHEMBL22191347 | 0.76 | PDE3B (0.60) | PDE3BPDE3AGRIA1CACNG8DYRK1A | |
| SCHEMBL2208549 | 0.75 | PDE3B (1.00) | PDE3BPDE3AJAK2CDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924296-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-09-17 | — | — | CN | disclosed |