Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.68 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25196901 | 0.83 | MAPT (0.76) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8484337 | 0.83 | MAPT (0.76) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25193659 | 0.83 | MAPT (0.76) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25185071 | 0.83 | MAPT (0.76) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8484340 | 0.83 | MAPT (0.76) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25232280 | 0.83 | MAPT (0.76) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8485080 | 0.81 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8485074 | 0.81 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23086310 | 0.81 | MAPT (0.88) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23086308 | 0.81 | MAPT (0.88) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118925-B | Preparation method and application of benzimidazole-2-ketone derivative | 中国人民解放军陆军军医大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-119118925-A | Preparation method and application of benzimidazole-2-ketone derivative | 中国人民解放军陆军军医大学 | 2024-12-13 | — | — | CN | disclosed |