Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174841 | 1.00 | PDE2A (0.42) | PDE2APDE1CSMN1; SMN2MAPK1TSHR | |
| SCHEMBL29175058 | 0.83 | GAA (0.43) | PDE2APDE1CSMN1; SMN2MAPK1TSHR | |
| SCHEMBL55774 | 0.79 | PDE2A (0.64) | PDE2ACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29174759 | 0.79 | PDE10A (0.43) | PDE2APDE1CSMN1; SMN2MAPK1TSHR | |
| SCHEMBL22521558 | 0.75 | ABL1 (0.45) | SMN1; SMN2MAPK1TSHRCYP1A2CYP2C9 | |
| SCHEMBL22805547 | 0.75 | PDE2A (0.50) | PDE2ACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29174833 | 0.75 | PDE1C (0.34) | PDE1CSMN1; SMN2MAPK1TSHRCYP1A2 | |
| SCHEMBL7904205 | 0.72 | PLK4 (0.41) | PDE2AMAPK1GAAALDH1A1 | |
| SCHEMBL2357706 | 0.71 | KDM4E (0.43) | PDE2APDE1CKMT2A | |
| SCHEMBL2189832 | 0.71 | ADORA3 (0.43) | PDE2ASMN1; SMN2MAPK1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249380-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |