Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 10/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31196244 | 1.00 | RIPK1 (0.57) | RIPK1PARP15PARP10 | |
| SCHEMBL31196115 | 1.00 | RIPK1 (0.57) | RIPK1PARP15PARP10 | |
| SCHEMBL31196232 | 0.93 | RIPK1 (0.51) | RIPK1PARP15PARP10 | |
| SCHEMBL31196165 | 0.93 | RIPK1 (0.51) | RIPK1PARP15PARP10 | |
| SCHEMBL31196131 | 0.92 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL31196374 | 0.92 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL31196108 | 0.90 | RIPK1 (0.54) | RIPK1PARP15PARP10 | |
| SCHEMBL31196507 | 0.90 | RIPK1 (0.54) | RIPK1PARP15PARP10 | |
| SCHEMBL31196372 | 0.85 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL31196298 | 0.85 | RIPK1 (0.51) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709716-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | claimed |
| WO-2024233554-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | claimed |
| EP-4709716-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233554-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |