Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15308686 | 1.00 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL19816466 | 1.00 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL17040985 | 0.89 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL22070745 | 0.89 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL22070743 | 0.89 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL663519 | 0.89 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL2374740 | 0.89 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL663520 | 0.89 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL14127654 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL14328059 | 0.86 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709716-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233554-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |